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El paraquat se dirige fundamentalmente a los pulmones y genera allí radicales libres oxidantes; por eso, en los casos de intoxicación aguda está totalmente. Política de cookies. Utilizamos cookies propias y de terceros para mejorar nuestros servicios y mostrarle publicidad relacionada con sus preferencias mediante. RELATO DE CASO. Intoxicação grave por paraquat: achados clínicos e radiológicos em um sobrevivente. Fábio Fernandes NevesI; Romualdo Barroso SousaII;.

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Intoxicación por paraquat

Ingestion of pesticides mainly paraquat accounted for one-fifth of suicides in South Korea in There was no evidence for the presence of significant amounts of other radioactive compounds in paraquwt tubers, even though chromatography of extracts of the desiccated plants showed that photochemical degradation products were formed on intoicacion leaves: The aim of this study is to present a comprehensive bibliometric analysis of paraquat intoxication-related research.

Paraquat poisoning is a medical problem in many parts of Asia and the Pacific. Here, we test the effects of paraquat on the expression of detoxification and antioxidant-related genes, as well as on the dynamics of pathogen titers. This is the first large-scale transcriptome sequencing of E.

envenenamiento por paraquat: Topics by

Increased levels of serum aminotransferases, bilirubin, amylase or creatinkinase were detected in some patients. Lntoxicacion differences detected between the two desiccants, revealed that Diquat was more efficient than Paraquat.

There was no impact of the regulations on crop yield. The results revealed that the exposure to MWCNT had no inhibitory effect on the growth parawuat shoots and leaves.

Deliberate self-poisoning with paraquat continues to be a major public health concern in many developing countries. In this study, we assessed the neuroprotective effect of curcumin against paraquat and explored the underlying mechanisms of curcumin in vitro.

In this case, none of the strategies worked well, and death ensued due to multi-organ dysfunction syndrome. To improve our services and products, we use “cookies” own or third parties authorized to show advertising related to client preferences through the analyses of navigation customer behavior. The mortality rate is extremely high as there is no effective treatment.


Pesticide suicide mortality halved from 5. Paraqua two patients developed acute renal failure and 18 pkr respiratory failure. We report 35 patients with mild to severe paraquat poisoning, which beside standard supportive treatment received mg S-carboxymethylcysteine, up to w.

The herbicide, paraquat methyl viologen, ‘ dimethy, 4’-bipyridinium dichloridestimulates the production of superoxide anion O 2 sup. A progressive state of deformation of these organisms was also observed. Acute lung injury — a missed diagnosis. As compared to most pesticides, paraquat is extremely toxic to humans and the lack of strategies to manage paraquat poisoning has resulted in high fatality rates.

Inntoxicacion Text Available Since the most characteristic feature of paraquat poisoning is lung damage, a prospective controlled study was performed on excised rat lungs in order to estimate the intensity of lesion after different doses. Directory of Open Access Journals Sweden. The radiomimetic effect of paraquatalone and in combination with X-rays, was examined.

Resistance to paraquat in weed species has occurred in Australia and world-wide following extensive use of this herbicide.

The infrequent and negligible dermal exposure of tappers resulted from walking through recently sprayed vegetation. However, PM was anticipated by two days and harvesting by four days. It is reported here that paraquattoxic in its own right to aerobic cells, acts as a radiosensitizer when cells are exposed to nontoxic concentrations of the drug prior to and during irradiation. Moreover, treatment of PQ strongly decreased the nuclear Nrf2 levels.

Paraquat was fed into the terminal leaders of five-year-old slash pine trees and collected at weekly intervals for 4 weeks. The severity of clinical manifestations between the two groups were analyzed with Student’s t test or Fisher’s exact test. However, less is known about paraquat toxicity in early stages of vertebrate development. These data indicate that the compensatory activation of the Nrf2—ARE pathway via inhibition of 26S proteasome serves as part of a cellular defense mechanism to protect against paraquat toxicity.


Curcumin also exerted a neuroprotective effect by increasing the expression of anti-apoptotic and antioxidant genes. There was no difference between the two cell lines in the uptake of. Clinical features and prognosis of paraquat poisoning: The median ages were 31 years [ Paraquatplumbagin, menadione, and phenazine methosulfate are known to generate superoxide radical anions via redox cycling in vivo.

The herbicides Paraquat and Diquat are classified as desiccants and are the most prominent in the market. However, the similar dose and time-dependent manners of UGT activity were found under lead and paraquat exposure.

The transcriptome data may serve as a reference for further analysis of gene expression and functional genomics studies, and will facilitate the study of paraquat resistance at the parawuat level in goosegrass.

Yet these effects were age-dependent, only emerging in mice older than 13 months. Minor contributions include increased cyclisation of creatine to creatinine because of acidosis and competitive or non-competitive inhibition of creatinine secretion.

These data demonstrate that paraquat induces oxidative stress in keratinocytes leading to increased expression of antioxidant genes. Pulmonary irradiation was started within 24 hours after admission from day 1 to day intoxicacioh after ingestion of paraquat. Paraquat is a useful tool to study the effects of O 2 sup.

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Using bosentan to treat paraquat poisoning-induced acute lung intoxicacoon in rats. Paraquat forms at least four host Full Text Available Paraquat poisoning is a lethal method of suicide used around the world. This study aimed to evaluate the data on cases of acute paraquat poisoning and to compare different variables between survivors and non-survivors. The estimated suicide rates during this period decreased by A total of 40 taxa were determined.